Education6 min read
What Are Peptides? A Beginner's Guide to How They Work
Peptides are everywhere in biology — but most explanations make them harder to understand than they need to be. Here's the plain-English version.
Read Article →Resources
The Peptide Library
Science-backed education for biohackers. Plain English. No hype.
Featured Guides
Featured
BPC-157: What the Research Actually Says
The most popular recovery peptide. Here's the full breakdown.
Read Guide →FeaturedIpamorelin: The Clean GH Secretagogue for Fat Loss, Muscle, and Anti-Aging
The cleanest growth hormone trigger in the stack.
Read Guide →FeaturedGHK-Cu: The Copper Peptide for Skin Rejuvenation, Wound Healing, and Longevity
Skin, wound healing, and longevity — one peptide does all three.
Read Guide →Research8 min read
BPC-157: What the Research Actually Says
One of the most discussed peptides in the biohacking community. Here's an honest look at what the science actually shows.
Read Article →Comparison8 min read
TB-500 vs BPC-157: What's the Difference?
Both peptides are studied for tissue repair — but they work differently. Here's an honest side-by-side breakdown.
Read Article →Protocols7 min read
Peptide Dosing: How to Think About Protocols
Peptide dosing sits in genuinely complicated territory — understanding why it's complicated is the first step toward building a protocol that actually makes sense for you.
Read Article →Anti-Aging6 min read
GHK-Cu: The Anti-Aging Peptide Backed by Research
GHK-Cu is one of the most researched anti-aging peptides. Here's what the science actually says about this copper-bound tripeptide and why longevity researchers keep coming back to it.
Read Article →GH Secretagogues7 min read
Ipamorelin vs CJC-1295: Which GH Secretagogue Is Right for You?
A clear comparison of two of the most popular growth hormone secretagogues — how they work, how they differ, and why researchers stack them.
Read Article →GH Peptides7 min read
Sermorelin Peptide Guide: The Smarter Approach to GH Optimization
Sermorelin is a GHRH analog that stimulates your pituitary to produce GH naturally — not synthetically. Here's what the research shows and why biohackers prefer it.
Read Article →Longevity6 min read
NAD+ and Peptides: Building a Complete Longevity Stack
NAD+ precursors and research peptides like GHK-Cu and BPC-157 address aging at different biological depths. Here's how they fit together and what the science actually shows.
Read Article →Research7 min read
BPC-157 Dosage: What the Research Suggests
Animal studies on BPC-157 use a fairly consistent dosing range, but translating that to human protocols is more nuanced than most sources admit. Here's what the research actually shows.
Read Article →Beginner6 min read
Peptide Safety: What You Need to Know Before You Start
Peptides have a generally favorable safety profile in research — but "generally favorable" comes with important caveats about sourcing, context, and what the research actually covers.
Read Article →Protocols8 min read
How to Reconstitute Peptides: Step-by-Step Guide (With Dosing Math)
If you have a peptide vial and aren't sure what to do next, this is the guide. Covers supplies, a seven-step reconstitution process, concentration math with worked examples, storage rules, and six common mistakes to avoid.
Read Article →Practical Guide8 min read
How to Store Peptides: Temperature, Shelf Life, and Common Mistakes
Learn how to store peptides correctly — lyophilized vs reconstituted rules, ideal temps, shelf life, common mistakes, and peptide-specific storage tips.
Read Article →Fat Loss9 min read
Best Peptides for Fat Loss: What the Research Says
The best peptides for fat loss, ranked by research. Ipamorelin, CJC-1295, AOD-9604, Tesamorelin, and more — science-backed, no-hype breakdown.
Read Article →Muscle Growth9 min read
Best Peptides for Muscle Growth: What Actually Works
The best peptides for muscle growth, ranked by evidence. Ipamorelin, CJC-1295, BPC-157, TB-500, and more — science-backed breakdown for serious results.
Read Article →Sleep & Recovery9 min read
Peptide Protocols for Sleep & Recovery: What Actually Works
Discover the best peptides for sleep and recovery — DSIP, Ipamorelin, CJC-1295, BPC-157, and Epithalon. Science-backed bedtime protocols for deeper sleep and faster recovery.
Read Article →Anti-Aging9 min read
Peptide Protocols for Anti-Aging: A Complete Stack Guide
Discover the best peptides for anti-aging — GHK-Cu, Epithalon, BPC-157, Ipamorelin, TA-1, and Selank. Science-backed anti-aging peptide protocols from beginner to advanced longevity stacks.
Read Article →Women's Health9 min read
Peptides for Women: What's Actually Safe and Effective
Peptides for women: what's actually safe and effective for skin, hormonal health, longevity, and recovery. Science-backed protocols from beginner to advanced.
Read Article →Hormones & Endocrinology9 min read
Peptides and Hormones: What You Need to Know
Do peptides affect hormones? Learn how peptides interact with testosterone, cortisol, thyroid, and the HPA axis — and what bloodwork to track.
Read Article →Protocols9 min read
Peptide Cycling: How to Structure Your Protocol
Learn how to structure peptide cycling protocols for maximum results. Avoid receptor desensitization with proper on/off windows for every major peptide.
Read Article →Science & Mechanisms9 min read
Peptide Bioavailability: Oral vs Subcutaneous vs Nasal (Which Actually Works?)
Do peptides have to be injected? Learn the real story on peptide bioavailability — why oral peptides mostly don't work, how subcutaneous injection delivers near-100% absorption, and which peptides are actually viable intranasally.
Read Article →Getting Started8 min read
How Long Do Peptides Take to Work? Setting Realistic Expectations
Most people quit right before results arrive. Here's the honest timeline for every major peptide — what to expect in the first 2 weeks, 2 months, and beyond.
Read Article →Getting Started10 min read
Peptides for Beginners: Your First 30 Days — A Complete Starter Guide
New to peptides? This complete 30-day starter guide walks you through the three best beginner peptides, a week-by-week protocol, what to expect and when, and the most common mistakes that derail first-timers.
Read Article →Safety9 min read
Peptide Side Effects: What's Normal, What's Not — And When to Stop
The honest, comprehensive guide to peptide side effects — what to expect, what's a red flag, and exactly when to stop.
Read Article →Immune Health9 min read
Thymosin Alpha-1 (TA-1): The Immune Peptide You Haven't Heard Of
Thymosin Alpha-1 (TA-1) is the immune peptide immunologists have used clinically for decades — approved in 37+ countries for hepatitis, cancer, and infections. Here's what the biohacker community is finally catching on to.
Read Article →Cognitive Performance10 min read
Selank and Semax: Peptides for Anxiety, Focus, and Cognitive Performance
Most biohacker protocols obsess over body composition, recovery, and hormones — but ignore the brain. Selank and Semax are the two most researched peptide nootropics on earth, developed in Russia and approved for clinical use. Here's what they do, how they work, and how to use them.
Read Article →Immune Health9 min read
KPV Peptide: The Potent Anti-Inflammatory You've Never Heard Of
KPV is a tripeptide fragment of alpha-MSH with powerful anti-inflammatory effects on the gut, skin, and immune system. Here's what the research shows.
Read Article →Recovery & Repair10 min read
Peptides for Gut Health: BPC-157, Leaky Gut, and the Gut-Brain Axis
BPC-157 is the best-researched peptide for gut healing — but it's not the only one. Here's how peptides repair intestinal permeability, calm inflammation, and support the gut-brain axis.
Read Article →Immune Health & Longevity10 min read
Humanin: The Neuroprotective Peptide Encoded in Your Mitochondrial DNA
Humanin is a mitochondrial-derived peptide with powerful neuroprotective and longevity effects. Learn how it works, what the research shows, and how to stack it.
Read Article →Immune Health / Longevity9 min read
Epithalon: The Anti-Aging Peptide That Activates Telomerase
Epithalon is a four-amino-acid peptide that activates telomerase — the enzyme that rebuilds the protective caps on your chromosomes. Here's the science, the dosing, and an honest look at what 35 years of Russian longevity research actually shows.
Read Article →Anti-Aging & Longevity11 min read
Peptides for Skin: GHK-Cu, BPC-157, and Collagen Protocols
Topical peptide creams are everywhere. Systemic peptide protocols are something else entirely. Here's the science of how GHK-Cu, BPC-157, and GH secretagogues actually rebuild skin from the inside out — collagen synthesis, fibroblast stimulation, and the stack worth knowing.
Read Article →Longevity & Anti-Aging10 min read
MOTS-c: The Mitochondrial Peptide for Metabolic Health and Longevity
MOTS-c is the first peptide ever discovered encoded in mitochondrial DNA — and it might be the missing layer in your longevity stack. Here's the science, the dosing, and how it stacks with NAD+, BPC-157, and Epithalon.
Read Article →Longevity & Anti-Aging10 min read
SHLP2: The Mitochondrial Peptide Targeting Metabolism and Aging
SHLP2 is one of six small humanin-like peptides hidden in your mitochondrial genome — and the one with the most interesting research outside of MOTS-c and Humanin. Here's the mechanism, the honest research ceiling, and where it slots into a serious longevity stack.
Read Article →Longevity & Anti-Aging10 min read
SHLP6: The Mitochondrial Peptide for Eye Health and Skin Aging
SHLP6 is the mitochondrial-derived peptide with the strongest expression in retinal tissue — and one of the only MDPs with a real signal in skin biology. Here's the mechanism, the honest research ceiling, and where it slots into a longevity stack.
Read Article →Performance & Muscle11 min read
Follistatin: The Peptide That Suppresses Myostatin for Muscle Growth
Learn how follistatin works to suppress myostatin, boost muscle growth, and support recovery. Science-backed guide for biohackers and fitness enthusiasts.
Read Article →Performance & Wellness11 min read
PT-141 (Bremelanotide): The Peptide for Sexual Health and Libido
PT-141 (bremelanotide) is the first FDA-approved peptide for female sexual dysfunction. How it works, why it differs from Viagra, dosing, and safety.
Read Article →Performance & Body Composition13 min read
AOD-9604: The Fat Loss Peptide That Targets Stubborn Body Fat
AOD-9604 is the C-terminal fragment of human growth hormone, isolated specifically for fat metabolism. Here's how it works, what the research shows, and how it compares to full hGH.
Read Article →Immune Health & Longevity13 min read
LL-37: The Antimicrobial Peptide That Bridges Immunity and Healing
LL-37 is the human body's only cathelicidin — a host defense peptide that kills pathogens directly and orchestrates immune repair. Here's what the research actually shows, where the nuance lives, and why it isn't a 'more is better' molecule.
Read Article →Growth Hormone / Anti-Aging13 min read
Sermorelin: The Anti-Aging Peptide That Restores Natural Growth Hormone
Sermorelin is the original FDA-approved GHRH analogue — a fragment of the body's own growth hormone-releasing hormone that prompts the pituitary to restore youthful GH levels rather than replace them. Here's the mechanism, the clinical record, and how it compares to HGH, CJC-1295, and ipamorelin.
Read Article →Cognitive & Anxiolytic12 min read
Selank: The Russian Nootropic Peptide for Anxiety and Cognitive Enhancement
Selank is a synthetic heptapeptide developed in Russia that delivers anxiolytic and nootropic effects without sedation. Here's the science, the mechanism, the protocols, and how it compares to Semax.
Read Article →Cognitive13 min read
Semax: The Russian Nootropic Peptide for Focus, Memory, and Brain Recovery
Semax is an ACTH(4-7) analogue developed in Russia that drives BDNF upregulation, dopaminergic tone, and neuroplasticity. The signal amplifier of the nootropic stack — and Selank's functional companion.
Read Article →Cognitive15 min read
Semax Peptide: The Complete Science on Focus, Memory, and Neuroprotection
The complete research guide to Semax — ACTH(4-7)PGP analog, BDNF upregulation, dopaminergic tone, HIF-1α neuroprotection, stroke recovery, and cognitive stack protocols. Built in a Russian space program lab. Used in biohacker stacks worldwide.
Read Article →Cognitive14 min read
Dihexa: The Most Potent Nootropic Peptide for Memory and Cognitive Repair
Dihexa is an HGF/c-Met mimetic developed at Washington State University as an Alzheimer's drug candidate. The most structurally ambitious nootropic peptide available — and the only one targeting synaptogenesis directly.
Read Article →Immune Health14 min read
Thymosin Alpha-1: The Immune-Modulating Peptide for Infection, Cancer Support, and Longevity
Thymosin Alpha-1 (TA-1) is the most clinically validated immune peptide — approved in 35+ countries for hepatitis, cancer adjunct therapy, and immune senescence. Here's everything you need to know.
Read Article →Hormonal & Fertility14 min read
Kisspeptin: The Master Hormone Regulator for Fertility, Libido, and Metabolic Health
Kisspeptin sits at the top of the HPG axis — above testosterone, above LH, above GnRH itself. The master hormone regulator most biohackers never find. Mechanism, human research, dosing, stacking, and why pulsatile delivery is non-negotiable.
Read Article →Skin & Regeneration15 min read
GHK-Cu: The Copper Peptide for Skin Rejuvenation, Wound Healing, and Longevity
GHK-Cu is the copper peptide behind younger-looking skin, faster wound healing, and anti-aging longevity research. Here's what the science actually says.
Read Article →GH & Performance14 min read
CJC-1295 / Mod-GRF 1-29: The Ipamorelin Stack Peptide for Sustained GH Release
CJC-1295 and Mod-GRF 1-29 are GHRH analogs that amplify your natural GH pulses. Here's how they work, how they differ, and why biohackers stack them with Ipamorelin.
Read Article →GH & Performance16 min read
Ipamorelin: The Clean GH Secretagogue for Fat Loss, Muscle, and Anti-Aging
Ipamorelin is the selective GH secretagogue that releases growth hormone without spiking cortisol, prolactin, or appetite. Here's what the science says.
Read Article →Cognitive & Longevity14 min read
Pinealon: The Pineal Peptide for Brain Protection, Circadian Health, and Longevity
Pinealon is the tripeptide that restores the pineal gland itself — not just supplements melatonin. The upstream lever for sleep, neuroprotection, and longevity.
Read Article →Immune Health & Longevity14 min read
Thymalin: The Thymus Peptide for Immune Restoration and Longevity
Your thymus shrinks from puberty onward and by 65 it's mostly fat. Thymalin is the closest thing we have to hitting undo — Khavinson's thymus peptide.
Read Article →Repair & Recovery15 min read
TB-500 (Thymosin Beta-4): The Injury Recovery Peptide for Athletes and Biohackers
Before BPC-157 blew up, recovery insiders were quietly running TB-500. Here's the full breakdown — mechanism, evidence, stack, and protocol.
Read Article →Recovery9 min read
BPC-157 vs TB-500: Which Recovery Peptide Is Right for You?
Both are elite recovery peptides — but they work completely differently. Here's how to choose, and why serious biohackers use both.
Read Article →GH & Performance8 min read
Tesamorelin: The FDA-Approved GHRH Peptide for Fat Loss and GH Optimization
Tesamorelin is the only FDA-approved GHRH peptide. Learn how it works, what the clinical research shows, and how it compares to other GH secretagogues.
Read Article →GH & Performance13 min read
Hexarelin: The Potent GHRP for Muscle, Cardio, and GH Pulse
Hexarelin is the most potent GHRP by GH pulse amplitude — and the only one that binds cardiac receptors directly. Here's the mechanism, the cardiac research, desensitization protocols, and how it compares to Ipamorelin, GHRP-2, and GHRP-6.
Read Article →Repair & Recovery15 min read
Pentadeca Arginate (PDA): The Next-Generation Repair Peptide
BPC-157 changed how biohackers think about repair. PDA might be the version that actually ships — same core pathways, better stability, and real oral bioavailability.
Read Article →Hormonal Health13 min read
Gonadorelin: The Peptide Behind Natural Testosterone and Fertility Support
Gonadorelin is synthetic GnRH — the master hormone that sits at the very top of the HPG axis, telling your pituitary to release LH and FSH. For TRT users, biohackers, and anyone trying to preserve fertility, it's the upstream lever most people never think to pull.
Read Article →GH & Performance13 min read
GHRP-2: The High-Amplitude GH Secretagogue for Muscle, Fat Loss, and Recovery
GHRP-2 is the high-output middle ground in the GHRP class — stronger GH pulse than Ipamorelin, cleaner than GHRP-6, and backed by more clinical trial data than almost any peptide in the growth hormone space. Here's how it works, what the research shows, and how to use it.
Read Article →Sexual Health12 min read
Melanotan II: The Tanning Peptide for Skin Pigmentation, Libido, and Fat Loss
Melanotan II activates melanocortin receptors to drive skin tanning, libido, and appetite suppression. Here's the honest science on the melanin pathway — mechanism, dosing, side effects, and what the research actually shows.
Read Article →Sexual Health12 min read
PT-141 (Bremelanotide): The FDA-Approved Peptide for Sexual Health and Libido
PT-141 is the only FDA-approved melanocortin-based peptide for sexual dysfunction — approved as Vyleesi in 2019. Unlike Viagra, it works centrally, activating MC3R/MC4R in the hypothalamus to drive desire at the neurological level. Mechanism, clinical evidence, dosing, and stack context.
Read Article →Mitochondrial Health12 min read
MOTS-c: The Mitochondrial Peptide That Mimics Exercise and Extends Longevity
MOTS-c is encoded directly in mitochondrial DNA — not nuclear DNA — making it one of the most unusual peptides in the body. It activates AMPK, mimics the molecular signature of exercise, and may be part of why regular training is anti-aging. Here's the honest science.
Read Article →Mitochondrial Health13 min read
Humanin: The Neuroprotective Mitochondrial Peptide for Brain Health and Longevity
Humanin is the mitochondrial-derived peptide that blocks neuronal death — discovered in an Alzheimer's screen and linked to centenarian longevity genetics. Here's the mechanism, the research, and how it fits into a serious longevity stack.
Read Article →Mitochondrial Health13 min read
SS-31 (Elamipretide): The Mitochondrial Membrane Peptide for Energy, Aging, and Heart Health
SS-31 (Elamipretide / MTP-131) is the only mitochondrial peptide with Phase II/III human clinical trial data — and it works at the most upstream point in the energy chain: the inner mitochondrial membrane itself. Cardiolipin science, AURORA-HF data, and bioenergetic stack context.
Read Article →Mitochondrial Health16 min read
Mitochondrial Peptides: The Complete Guide to MOTS-c, Humanin, and SS-31 (Elamipretide)
Discover how MOTS-c, Humanin, and SS-31 target mitochondrial dysfunction from three different angles — metabolic signaling, neuroprotection, and inner membrane structural integrity. Complete research guide with stack protocols and clinical evidence.
Read Article →Hormonal Health14 min read
Kisspeptin-10: The Reproductive Peptide for Hormonal Health, Fertility, and Libido
Kisspeptin-10 is the upstream gatekeeper of the entire HPG axis — sitting above GnRH, LH, and testosterone in the signaling cascade. Here's the KISS1R mechanism, the KNDy neuron system, human trial data from Seminara 2003 to Abbara 2020, and how it stacks with Gonadorelin, PT-141, and Epithalon.
Read Article →GH & Performance18 min read
Growth Hormone Peptides: The Complete Guide to GH Secretagogues (Sermorelin, Ipamorelin, CJC-1295, GHRP-2, Tesamorelin, Hexarelin)
Growth hormone peptides restore natural pulsatile GH release — working with the body's feedback loops rather than overriding them. This complete guide covers all six major GH secretagogues: mechanisms, clinical evidence, stacking logic, and protocols from beginner to advanced.
Read Article →Immune Health17 min read
Immune Health Peptides: The Complete Guide to LL-37, Thymosin Alpha-1, and Thymalin
Your immune system has a peptide control layer most people never hear about. LL-37 defends the front line, Thymosin Alpha-1 rebuilds adaptive immunity, and Thymalin resets the thymic aging clock. Complete research guide with stack protocols and clinical evidence.
Read Article →Cognitive & Nootropic18 min read
Cognitive Peptides: The Complete Guide to Nootropic Peptides for Brain Health and Mental Performance
The complete research guide to nootropic peptides — Selank, Semax, Dihexa, and Pinealon. Mechanisms, stacks, and protocols for brain health and mental performance.
Read Article →Repair & Recovery20 min read
Repair & Recovery Peptides: The Complete Guide to BPC-157, TB-500, and Pentadeca Arginate (PDA)
BPC-157, TB-500, and PDA each target a different phase of the tissue repair cascade. This is the complete guide — mechanisms, clinical evidence, and the stack protocols that tie all three together.
Read Article →Fat Loss20 min read
Fat Loss Peptides: The Complete Guide to AOD-9604, CJC-1295, and Tesamorelin
The complete research guide to fat loss peptides — AOD-9604, CJC-1295/Mod-GRF, and Tesamorelin. Three peptides, three mechanisms, one complete fat loss stack. Protocols from beginner recomposition to advanced visceral fat targeting.
Read Article →Skin & Regeneration14 min read
GHK-Cu: The Complete Science on Skin Regeneration, Wound Healing, and Anti-Aging
GHK-Cu is the copper tripeptide discovered in 1973 that modulates over 4,000 genes — driving collagen remodeling, wound healing, hair regrowth, and antioxidant defense. Here's the complete research breakdown.
Read Article →Immune Health15 min read
LL-37: The Human Cathelicidin Peptide for Immune Defense, Gut Health, and Inflammation
LL-37 is the only cathelicidin the human body makes — a host defense peptide that kills pathogens directly, modulates inflammation, reinforces the gut barrier, and accelerates wound healing. Here's the complete research breakdown.
Read Article →Immune Health16 min read
Thymosin Alpha-1: The Immune Regulator for Viral Defense, Cancer Support, and Longevity
Thymosin Alpha-1 (Tα1) is approved as Zadaxin in 35+ countries yet remains unapproved in the US despite completing Phase III trials. It is the most clinically studied immunomodulatory peptide in existence. Complete breakdown: mechanisms, viral defense data (HBV/HCV/COVID-19), cancer adjunct evidence, longevity protocols, and comparison to Thymalin.
Read Article →Sleep & Recovery15 min read
DSIP (Delta Sleep-Inducing Peptide): The Complete Science on Sleep, Recovery, and Stress Hormones
DSIP is a 9-amino-acid neuropeptide that improves deep sleep architecture, resets cortisol rhythms, and augments GH secretion — without sedation, without dependence, and without suppressing REM. Here's the complete research breakdown: mechanisms, dosing protocols, and how it compares to melatonin, benzos, and Z-drugs.
Read Article →GH / Performance13 min read
Ipamorelin vs CJC-1295: The Complete Stack Guide for Growth Hormone Optimization
Ipamorelin triggers the GH pulse. CJC-1295 amplifies the signal. Together they produce a synergistic GH burst 2–10× greater than either alone — without suppressing your natural axis. Complete stack protocol, dosing, cycling, and results by goal.
Read Article →Cognitive & Nootropic14 min read
Semax vs Selank: Which Russian Nootropic Peptide Is Right for You?
Semax is energizing and BDNF-driven. Selank is calming and GABAergic. Both came from the same Moscow lab. Here's how to choose — and why biohackers stack them.
Read Article →Longevity15 min read
Epithalon vs Thymalin: Which Khavinson Peptide Is Right for You?
Both bioregulator peptides came from the same St. Petersburg lab and both extend lifespan in animal models — but they work on completely different systems. Here's how to choose and why serious longevity protocols use both.
Read Article →GH / Performance14 min read
Sermorelin vs Ipamorelin: Which GH Peptide Is Right for You?
Sermorelin and Ipamorelin both restore natural growth hormone — but through completely different receptors with different strengths. Here's how to choose between them as your first GH peptide, and why they actually stack perfectly.
Read Article →Fat Loss14 min read
AOD-9604 vs Tesamorelin: Which Fat Loss Peptide Is Right for You?
AOD-9604 burns fat directly via beta-3 adrenergic lipolysis — no IGF-1, no GH axis. Tesamorelin is FDA-approved and drives visceral fat loss through a restored GH pulse. Same category, completely different mechanisms. Here's how to choose.
Read Article →Repair & Recovery15 min read
BPC-157 vs Ipamorelin: Repair vs Growth Hormone — Which Do You Actually Need?
BPC-157 repairs tissue locally — VEGF, NO synthase, collagen rebuilding at the injury site. Ipamorelin fires a GH pulse systemically — IGF-1, satellite cells, protein synthesis everywhere. Same recovery improvement, completely different biology. Here's how to choose.
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